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Hansmann Begins International Collaboration with von Neumann Institute

January 10, 2006

Proteins in Silico Poster

Proteins in Silico

Click to enlarge poster.

Protein

MTU has started a collaboration with the John von Neumann Institute for Computing (NIC), the premier supercomputer center in Germany. As part of this collaboration, Prof. Dr. Ulrich H.E. Hansmann will build up a new research group "Computational Biology and Biophysics" at NIC. Dr. Hansmann will keep his position and research group at MTU.

The aim of the project with NIC is to study the physics of proteins using supercomputers such as JUMP, BlueGene or Cray-XD1 at NIC. Proteins are "working horses" in a cell that transport molecules, regulate chemical processes, or fight infections. These various functions depend on the specific structure of a protein and the joint research project will investigate the mechanism by that a protein folds into its active form. This problem is not only of academic interest as mis-folded proteins presumably cause a number of neurodegenerative diseases such as Alzheimer or BSE. A detailed knowledge of the relation between the chemical composition of a protein (which is specified in the genome) and its structure and function would enable the design of novel drugs with customized properties and minimized side effects. Use of proteins to assemble nanostructures is another research area of the project.

Related Links

Uli Hansmann Faculty Page

Hansmann Research Page

Computational Nano - and Biophysics Website

John von Neumann Institute for Computing

In 790 Chinese mathematicians used the method of finite differences to solve equations.

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